Gastric Reflux Is an Independent Risk Factor for Laryngopharyngeal Carcinoma

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Gastric reflux is an independent risk factor for laryngopharyngeal carcinoma.

BACKGROUND Gastric reflux can reach into the upper airway, inducing cellular damage in the epithelial lining. This condition is believed to be a risk factor for development of laryngopharyngeal squamous cell carcinoma (LPSCC), although the literature is conflicting. METHODS To better clarify this relationship, we assessed the association of self-reported heartburn history and medication use a...

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Laryngopharyngeal Reflux

1Department of Otolaryngology-Head Neck Surgery, Queen Alexandra Hospital, Portsmouth PO63LY, UK 2Department of Otolaryngology, Aristotle university of Thessaloniki, Thessaloniki, Greece 3Department of Otolaryngology-Head Neck Surgery, The Freeman Hospital, Newcastle Upon Tyne, UK 4Department of Otolaryngology-Head Neck Surgery, Schwarzwald-Baar Hospital, Villingen-Schwenningen, Germany 5Depart...

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Is laryngopharyngeal reflux related to functional dysphonia?

OBJECTIVES Laryngopharyngeal reflux (LPR) may be a contributing factor in chronic hoarseness. The association of LPR with functional dysphonia (FD), the most common voice clinic diagnosis, is unknown. We attempted to determine whether patients with FD have a higher rate of laryngeal exposure to acidic stomach contents than do healthy volunteers. METHODS We recruited through the voice clinic 2...

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Laryngopharyngeal Reflux Disease – LPRD

INTRODUCTION Laryngopharyngeal reflux disease (LPRD) referes to an inflammatory reaction of the mucous membrane of pharynx, larynx and other associated respiratory organs, caused by a reflux of stomach contents into the esophagus. LPRD is considered to be a relatively new clinical entity with a vast number of clinical manifestations which are treated through different fields of medicine, often ...

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Goiter and Laryngopharyngeal Reflux

The purpose of this study is to look at the prevalence of laryngopharyngeal reflux disease in patients with goiter in a group of 52 patients with goiter. All participants were asked to respond to the 9 questions on the Reflux Symptom Index (RSI). A diagnosis of LPRD based on symptoms was made for any RSI score above 10. The average score of every question was computed for all patients with goit...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2013

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-13-0183